Novel domains and repeats in nucleolar proteins

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No.	Description	Name	Size (AA)	Members
NUC001	central domain in Nop56/SIK1-like proteins	NOSIC	53	49
NUC002	characteristic domain in GAR1-like snoRNPs	GAR1L	61	20
NUC003	Treacher Collins-Franceschetti syndrome 1 protein tandem repeat	TCOFD	65	3
NUC004	characteristic repeat of p68-like RNA helicases	P68HR	35	7
NUC006	characteristic repeat of proliferating cell nuclear antigen P120	P120R	23	3
NUC007	KI67/Chmadrin-repeat	KI67R	113	3
NUC008	novel domain in poly(ADP-ribose)-synthetases; located between zf-PARP domains and BRCT repeats	PADR1	57	16
NUC009	novel domain in poly(ADP-ribose) polymerases; associated with zf-PARP, BRCT, SAM, PARP and ankyrin repeats/domains	PADR2	76	35
NUC010	characteristic domain in UVSB PI-3 kinase, MEI-41 and ESR1; associated with FAT, FATC, PI3_PI4_kinase modules	UME	110	11
NUC011	TruB_N/PUA domain associated N-terminal domain of Dyskerin-like proteins	DKCLD	59	27
NUC014	N-terminal domain in RNP K-like proteins with KH-domains	ROKNT	45	4
NUC016	N-terminal domain in 3'-5'-exonucleases with HRDC domain; putative exosome components; Polymyositis autoantigen 2	PMC2NT	98	7
NUC017	N-terminal domain of ribosomal L6 proteins	RL6NT	57	8
NUC018	N-terminal domain of ribosomal L30 proteins	RL30NT	71	21
NUC020	N-terminal domain of ribosomal S11/S17 proteins	RS11NT	39	44
NUC021	N-terminal domain of ribosomal S13/S15 proteins	RS13NT	60	37
NUC023	N-terminal domain of Ribosomal S4 / S4e proteins; associated with KOW domains	RS4NT	41	45
NUC029	C-terminal domain of DNA gyrases B / topoisomerase IV / HATPase proteins	DTHCT	110	15
NUC031	C-terminal domain in Bloom's syndrome DEAD helicase subfamily	BDHCT	41	4
NUC034	N-terminal domain in PHD/RING finger and chromo domain-associated helicases	CHDNT	55	7
NUC036	C-terminal domain A in PHD/RING finger and chromo domain-associated CHD-like helicases	CHDCT1	120	14
NUC038	C-terminal domain B in PHD/RING finger and chromo domain-associated CHD-like helicases	CHDCT2	180	11
NUC045	N-terminal domain in family of CCR4-associated factor-like proteins with zf-CCCH and R3H domains; part of the CCR4/NOT transcription complex	CAFNT	136	34
NUC046	C-terminal domain in Poly(A)-specific ribonucleases	PARNUCT	46	9
NUC056	domain in ILF3/p122/NF45 transcription factors; associated with dsrm repeats	IPN	154	43
NUC059	C-terminal domain of NONA and PSP1 proteins	NOPS	53	20
NUC060	SMC hinge region	SMChinge	153	86
NUC062	characteristic domain of CCAAT-box binding transcription factors and MAK21-like proteins; implications in ribosome biogenesis and transcription regulation	CBFMK21	40	19
NUC063	novel putative zinc-binding domain (CHHC motif) in RNP H and F; rrm repeat-associated	zf-RNPHF	36	6
NUC064	C-terminal repeat in RBM1-like RNA binding hnRNPs; associated with rrm repeats in the N-terminus	RBM1CTR	46	15
NUC068	central domain in Poly(rC)-binding proteins; associated with KH domain	PrCBPCN	132	14
NUC069	N-terminal domain in pre-mRNA splicing factors of PRO8 family	PRO8NT	155	13
NUC071	central domain in pre-mRNA splicing factors of PRO8 family	PROCN	426	13
NUC072	C-terminal domain in pre-mRNA splicing factors of PRO8 family	PRO8CT	129	13
NUC083	novel domain C-terminal to WD40 repeats in Dom34p-interacting protein 2 from yeast; role in regulation of translation	DIP2CT	103	8
NUC086	conserved region in proteins of the Bystin family; interaction with trophinin, tastin and cytokeratin; unusual occurence in nucleolar protein	BysCR	256	9
NUC087	C-terminal domain characteristic of NOG subfamily of nucleolar GTP-binding proteins	NOGCT	134	15
NUC091	N-terminal domain characteristic for subfamily of hypothetical nucleolar GTP-binding proteins similar to human NGP1	NGP1NT	134	14
NUC094	present in proteins of the Ferlin family; often central between two C2 domains	FerI	72	10
NUC095	central domain A in proteins of the Ferlin family	FerA	67	18
NUC096	central domain B in proteins of the Ferlin family	FerB	79	18
NUC098	central domain C in proteins of the Ferlin family	FerC	120	18
NUC102	C-terminal conserved domain of traube proteins	TRAUB	87	11
NUC103	central domain hypothetical nucleolar proteins of novel family defined by alignments NUC103/104	NUC103/4	156	8
NUC104	C-terminal domain hypothetical nucleolar proteins of novel family defined by alignments NUC103/104	NUC103/4	149	8
NUC105	N-terminal domain of maleless-like RNA helicase family	MLENT	128	6
NUC108	C-terminal domain of maleless-like RNA helicase family	MLECT	41	45
NUC109	central domain of proteins from DNA polymerase type V subfamily	DPOCT	71	7
NUC110	central domain between Ubox (RING-finger like) domain and WD40 repeats in spliceosome/cdc5p-associated proteins; possibly degenerated WD40 repeats	CDC5PAD	117	10
NUC111	N-terminal domain in pescadillo-like proteins with BRCA1 C-terminus domain	PESCNT	139	10
NUC114	N-terminal domain in UBF transcription factors; possibly degenerated HMG box	NUBF	100	9
NUC119	C-terminal domain in Penguin-like proteins associated with Pumilio repeats	CPL	159	3
NUC121	AARP2 central domain; weakly similar to GTP-binding domain of elongation factor TU	AARP2CN	91	18
NUC123	AARP2 family C-terminal domain	AARP2CT	208	19
NUC125	central conserved domain in novel family of hypothetical proteins defined by NUC125	NUC125	73	9
NUC126	novel family of hypothetical nucleolar proteins defined by NUC126	NUC126	194	12
NUC127	N-terminal domain in RNA-binding proteins of the NOP5 family	NOP5NT	68	27
NUC129	C-terminal domain in novel family of hypothetical nucleolar proteins defined by NUC129	NUC129	63	4
NUC130	N-terminal domain of novel nucleolar protein family defined by NUC130/133; weakly similar to TFIIF beta subunit	NUC130/3NT	52	8
NUC133	C-terminal domain of novel family of nucleolar proteins defined by NUC130/133	NUC130/3CT	114	11
NUC135	redefined Nle domain of a family of proteins founded by fly notchless protein and yeast microtubule-associated protein YTM1; located N-terminal to WD40 repeats	NLE	71	13
NUC136	novel C2HC-type zinc finger in LYAR-like cell growth-regulating proteins; associated with rrm domains; present in one or two copies per protein	zf-LYAR	62	8
NUC141	C-terminal domain in BING4 family of nucleolar WD40 repeat proteins	BING4CT	80	12
NUC142	characteristic KR-rich domain for novel family of nucleolar proteins; SAS10 is a derepressor of silencing; LCP5 is a U3 snRNP component; domain is combined with a basic leucine zipper in one protein	KRSL	69	12
NUC145	central domain in NNP1/RRP1-like proteins	NNRR	144	10
NUC152	C-terminal domain characteristic for RNA helicase II / Gu protein family	GUCT	108	14
NUC153	small domain in novel nucleolar protein family defined by NUC153	NUC153	30	8
NUC156	C-terminal domain in nucleolar proteins of family NUC156	NUC156	151	6
NUC160	characteristic C-terminal domain for Dbp10p subfamily of hypothetical RNA helicases	DBP10CT	68	8
NUC161	N-terminal domain of CARG-binding factor A-like proteins; combined with rrm domains	CBFNT	76	12
NUC162	characteristic domain N-terminal to ARID/BRIGHT domain in DNA binding proteins of Retinoblastoma-binding protein 1 family	RBB1NT	100	4
NUC164	N-terminal domain in MAK16-like proteins	MAK16NT	139	12
NUC167	central domain in nucleolar proteins of family NUC167	Y112CN	50	10
NUC168	central domain in nucleolar proteins of the multicopy repressor of ras (Mra) family	MRACN	79	16
NUC169	N-terminal domain in BOP1-like WD40 proteins	BOP1NT	286	9
NUC173	central domain of novel family of hypothetical nucleolar proteins defined by NUC173	NUC173	203	8
NUC176	C-terminal domain in Nopp140-like proteins	NOPP140CT	72	9
NUC177	N-terminal domain defining a novel family of nucleolar translational activator proteins with HEAT repeats	TAHNT	66	5
NUC185	characteristic C-terminal domain of DOB1/SKI2/helY-like DEAD box helicases	DSHCT	202	24
NUC188	novel domain in family POP1-like nucleolar proteins	POPLD	108	6
NUC189	characteristic domain in NUC189 family of nucleolar proteins	NUC189	90	9
NUC191	domain A in the catalytic subunit of DNA-dependent protein kinases	NUC191	515	4
NUC194	domain B in the catalytic subunit of DNA-dependent protein kinases	NUC194	399	4
NUC200	characteristic domain in U3 snRNP mpp10-like proteins	MPP10	88	7
NUC201	N-terminal domain in hypothetical nucleolar proteins with NUC202 tandem repeat	NUC201	86	4
NUC202	NUC202 repeat; characteristic for a novel family of nucleolar proteins	NUC202	76	4
NUC203	C-terminal domain in novel family of hypothetical nucleolar WD40 repeat proteins	NUC203	87	5
NUC205	characteristic domain for novel family NUC205 of nucleolar proteins	NUC205	44	3
NUC209	N-terminal domain of BAP28-like nucleolar proteins	BP28NT	286	6
NUC211	C-terminal domain of BAP28-like nucleolar proteins	BP28CT	171	6
NUC213	N-terminal domain in hypothetical nucleolar proteins of novel NUC213 family	NUC213	36	14